Early-life stress-induced gut dysbiosis is ameliorated by nicotinamide treatment
Srivastav, S.; Chaudhari, P. R.; Suryavanshi, S.; Pange, N.; Vaidya, V. A.; Anand, A.
Show abstract
Early life stress (ELS) in the form of adverse experiences in childhood results in multiple psycho-physiological pathologies during adulthood and accelerates aging. Such pathologies are recently observed to be alleviated upon nicotinamide treatment in a maternal separation model of ELS. We report a nicotinamide-driven amelioration of gut dysbiosis in middle-aged rodents with a history of neonatal maternal separation.
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