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Comprehensive Evaluation of Associations between Lifestyle Factors and Multiple Epigenetic Aging Indicators in the Japanese Population: A cross-sectional study
2026-02-09
epidemiology
Title + abstract only
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BackgroundEpigenetic clocks based on DNA methylation (DNAm) provide quantitative indicators of biological aging. However, the extent to which diverse lifestyle factors influence DNAm-based aging measures remains unclear, especially in Japanese populations. We aimed to evaluate the associations between 52 lifestyle-related factors and multiple epigenetic aging indicators, including six DNAm ages (Horvath, Hannum, PhenoAge, GrimAge, GrimAge v2, and PCPhenoAge specific to Japanese Population), the ...
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