First trimester serum Cystatin C level is a predictor of Preeclampsia: a prospective study

2025-12-08 nephrology Title + abstract only

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IntroductionThe pathogenesis of Preeclampsia (PE) remains enigmatic. A new concept of Shrunken Pore Syndrome (SPS) has been proposed, where in there is shrinking of pore size of the glomerulus. The ratio eGFRcystatin C / eGFRcreatinine < 0.6 is considered as SPS. Few studies show that SPS exists in pregnant ladies in the first trimester. A novel biomarker which can predict preeclampsia in the first trimester is the need of the hour. Hence this study was done. MethodCystatin C and creatinine lev...