Medicine

BackgroundErector spinae plane (ESP) block has been reported to provide analgesia in spine surgery in case reports or case series, and there have been no controlled studies to date evaluating its efficacy. We aimed to exam the roles of ESP block in lumbar surgery in a single center randomized control trial by injecting local analgesic into the interfacial plane between the erector spinae muscles and the transverse process under ultrasound guidance. MethodsConsecutive elective lumbar surgery pat...

BackgroundHysteroscopy is considered the gold standard for the evaluation and treatment of uterine and endometrial lesions, but the operation is accompanied by severe pain, so it needs to be performed under anesthesia. Currently, a new sedative drug, remimazolam tosilate, can be used in digestive endoscopy and bronchoscopy. We will study its effect on hysteroscopy and its impact on patient recovery time and hospital discharge time. MethodsNinety-five patients undergoing hysteroscopy were random...

BackgroundEffective postoperative analgesia is therefore critical for patients undergoing thoracoscopic surgery. Ultrasound-guided erector spinae plane block (ESPB) has demonstrated efficacy in reducing postoperative pain following thoracoscopic procedures; however, limited research exists regarding the minimum effective volume (MEV) of local anesthetic required. This study employed the biased coin up-and-down sequential method (BCD-UDM) to determine the MEV of 0.5% ropivacaine for ESPB in patie...

IntroductionThe optimal dosage of dexmedetomidine (DEX) as an adjuvant combined with ropivacaine for postoperative analgesia in laparoscopic myomectomy is still controversial. The main aim of this prospective clinical trial was to evaluate the analgesic effect and relevant adverse effects of different doses of dexmedetomidine applied locally for ropivacaine-induced bilateral transmuscular quadratus lumborum block (TQLB). MethodsTQLB was conducted using different doses of dexmedetomidine per sid...

PurposeTo investigate the correlation between perioperative oxygen concentration and postoperative organ damage and other adverse reactions in children undergoing neurosurgery. Materials and methodsThis study was a single-center retrospective cohort study that included 512 children undergoing neurosurgery, aged [≤]14 years old, and with an operative duration [≥]2 hours who were transferred to the Postanesthesia Care Unit (PACU) of the Department of Anesthesiology, Beijing Tiantan Hospital...

IntroductionWith the widely used technique of One Lung Ventilation (OLV) in patients throughout thoracic surgery, its unclear whether inhaled or intravenous anesthetics were associated with postoperative complications. The purpose of the current study is to compare the effects of intravenous and inhaled anesthetics on the postoperative complications within the patients suffering OLV. MethodsWe searched the related randomized controlled trials in PubMed\EMBASE\Medline and the Cochrane library up...

PurposeTo improve the management level of general anesthesia during bronchoscopy in the children with diffuse alveolar hemorrhage (DAH). MethodsA retrospective study was conducted in the children with DAH who had performed bronchoscopy under general anesthesia with spontaneous respiration by face mask ventilation initially from June 2021 to June 2022 in our hospital. Results1. Thirty-four children who had underwent 38 bronchoscopy procedures were included. 2. General anesthesia induction was p...

BACKGROUNDGiven a low first-pass success rate of the conventional SAX (short-axis) or LAX (long-axis) approach, ultrasound-guided radial artery cannulation in adults with radial artery diameter less than 2.2 mm may be still challenging. OBJECTIVETo assess the efficacy of modified long-axis in-plane(M-LAIP) versus short-axis out-of-plane (SAOP) or conventional palpation(C-P) approaches for ultrasound-guided radial artery cannulation. DESIGNA prospective, randomized and controlled trial. SETTIN...

PurposeTo explore the influence of preoperative vagus nerve block (VNB) on postoperative nausea and vomiting (PONV) in patients undergoing thoracic or abdominal laparoscopic surgery. MethodsPatients were randomly divided into the VNB group (V group, n=60) and the control group (C group, n=60). The V group received left VNB before anesthesia induction, while the C group did not receive any intervention. The incidence and severity of PONV within one day after surgery were compared between the two...

BackgroundPostoperative delirium (POD) is a common neurocognitive complication following major surgery, particularly in older adults and those undergoing liver resections. Neuroinflammatory mechanisms are considered central to its pathophysiology, yet molecular mediators remain poorly defined. Autoantibodies (aABs) targeting G protein-coupled receptors (GPCRs)--especially those relevant to neurotransmission--may contribute to POD by disrupting neuroimmune homeostasis. This study explored the per...

BackgroundValvular heart surgery is associated with considerable perioperative risks including hemodynamic instability, arrhythmias, renal dysfunction and prolonged ICU stay. Dexmedetomidine a selective 2-adrenoceptor agonist, provides sedation and sympatholysis and has been investigated as a cardioprotective adjunct. ObjectivesTo evaluate the effects of dexmedetomidine on intraoperative hemodynamic stability and postoperative outcomes in adult patients undergoing valvular replacement surgery. ...

ObjectiveTo compare the long-term prognosis of patients who experienced acute ST-segment elevation myocardial infarction and underwent either late percutaneous coronary intervention (PCI) within a period of 2 days to less than 1 week or more advanced PCI within 1 week to less than 1 month. MethodsWe enrolled 198 patients from Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, between June 2019 and August 2022. These patients had experienced acute ST-segmen...

Acupotomy, originally named Nine Needles in Ling Shu, was invented as a new type of TCM instrument in 1976, an innovative combination of acupuncture and surgical treatment. Its forward development is related to the Clinical effectiveness and safety. RCTs are gold standards in clinical practice and were welcomed in Acupotomy recently. The CONSORT Statement is set to guide the designing, analysis and interpretation of trials. But there havent been many Acupotomy RCTs until now, with few on qualit...

BackgroundA low first-pass success rate of radial artery cannulation was obtained when using the conventional palpation technique(C-PT) or ultrasound-guided techniques, we therefore evaluate the effect of a modified long-axis in-plane ultrasound technique (M-LAINUT) in guiding radial artery cannulation in adults. MethodsWe conducted a prospective, randomized and controlled clinical trial of 288 patients undergoing radial artery cannulation. Patients were randomized 1:1 to M-LAINUT or C-PT group...

BackgroundPost-anesthetic tracheal extubation can lead to critical adverse events (AEs) in children due to their intolerance to hypoxia. However, evidence from pediatric studies on the factors associated with safe tracheal extubation is limited. We will investigate the incidence and risk factors of AEs associated with tracheal extubation using real-world data from Japan. This study aims to test the following hypotheses: extubation-related AEs are associated with (a) several indicative signs of c...

BackgroundDuring neuraxial access attempts, loss-of-resistance technique with air may inadvertently become injection-of-air technique potentially leading to intracranial air. ObjectiveThe purpose of this retrospective study was to ascertain the incidence of radiologically visible intracranial air among peri-partum patients admitted to local Womens Hospital who underwent computed tomography/magnetic resonance imaging (CT/MR) of head/brain during their hospital stay at peri-partum floors over a s...

IntroductionChronic postsurgical pain (CPSP) after cardiac surgery is a significant concern. Despite the known association between acute pain and CPSP, advanced pain management strategies have not reduced its incidence. Preventing CPSP requires optimizing acute pain control and disrupting central sensitization. The side effects and risks associated with chronic use of current opioid-based cardiac anesthesia necessitate the adoption of multimodal analgesia. Regional anesthesia is a promising alte...

Study objectiveSubclavian vein cannulation in the infraclavicular region may be a preferred approach as it is associated with less infection than internal jugular or femoral venous access in critically ill patients. Short-axis view" has a problem that shaft of the puncture needle is not visualized and tip of the needle is only seen as dot; hence posterior wall of the vein puncture is always possible with short-axis approach. We have designed this study to know the ultrasonographic anatomy of ...

BackgroundPostoperative pain significantly impacts recovery and healthcare costs. Supraclavicular brachial plexus block (SCBPB) offers effective regional anesthesia but has limited duration. However, dexamethasone may enhance and prolong analgesia when used as an adjunct. Therefore, this study aimed to evaluate the effective of dexamethasone added to bupivacaine in prolonging postoperative analgesia. MethodA randomized clinical trial was conducted at Halibet National Referral Hospital, Eritrea,...

IntroductionFollowing surgery with general anesthesia, some children experience a prolonged emergence. We designed a prospective observational study in children undergoing general anesthesia who were monitored with the SedLine(R) Sedation Monitoring system (Masimo Corporation, Irvine, CA) to explore the hypothesis that the Patient State Index (PSI) obtained with this monitor could be inversely correlated with the duration of emergence after anesthesia. Materials and methodsProspective, observat...