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Nutri Complex 150+: a new and effective approach to facial rejuvenation

Privitera, A.; Ferruggia, G.; Contino, M.; Maugeri, S.; Zimbone, M.; Cardile, V.; Caruso, G.; Brundo, M. V.

2024-10-07 cell biology
10.1101/2024.10.05.616805 bioRxiv
Show abstract

Skin is the largest multifunctional human organ and possesses a complex multilayered structure with the ability to regenerate and renew. The key role in skin regeneration is played by fibroblasts, also playing an important role in wound healing process. We used different methods to evaluate on human fibroblasts the in vitro effects of a new compound called Nutri Complex 150+ (NC150+), containing a mixture of 20 different biologically active factors (GF20) and exosomes isolated and purified from bovine colostrum. NC150+ was able to significantly enhance cell proliferation/metabolic status of fibroblasts at both 24 and 48 hours compared to untreated (control) cells. NC150+ was also able to enhance the ability of human fibroblasts to close the wound scratch. Our findings demonstrate the ability of NC150+, based on a new technology called AMPLEX plus, to enhance cell proliferation/metabolic status of fibroblasts. The obtained results also suggest how NC150+ could be potentially effective in treating skin injury.

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