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NF-κB Mediated Disruption of Pancreatic Signaling Pathways and its Implications for the Risk of Pancreatic Adenocarcinoma: a systematic review

2024-08-08 oncology Title + abstract only
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ObjectiveThe objective of this study is to determine how NF-{kappa}B-mediated inflammation disrupts pancreatic signaling pathways and the resultant increase in the risk of Pancreatic Adenocarcinoma. BackgroundPancreatic adenocarcinomas severity and poor prognosis underscore the critical role of NF-{kappa}B-mediated inflammation in disease progression. NF-{kappa}B activation disrupts key pancreatic signaling pathways by promoting cell proliferation, inhibiting differentiation, and facilitating o...

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