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Interleukin-33 stimulates stress in the endoplasmic reticulum of the human myometrium via an influx of calcium during initiation of labor
2021-11-09
obstetrics and gynecology
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BackgroundInflammation is currently recognized as one of the major causes of premature delivery. As a member of the IL-1{beta} family, interleukin-33 (IL-33) has been shown to be involved in a variety of pregnancy-related diseases. This study aims to investigate the potential function of IL-33 in uterine smooth muscle cells during labor. MethodsSamples of myometrium from term pregnant ([≥]37 weeks gestation) women were frozen or cells were isolated and cultured. Immunohistochemistry and west...
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