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Integrative Proteomic and Metabolomic Signatures of Accelerated PhenoAge in the UK Biobank

2026-03-03 epidemiology Title + abstract only
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Aging is accompanied by molecular changes across multiple biological systems that contribute to functional decline and increased disease risk, but the underlying mechanisms and inter-individual variation remain poorly understood. We investigated whether multi-omics integration can reveal coordinated molecular processes associated with accelerated PhenoAge, a clinical biomarker-based estimate of biological aging. Using UK Biobank data from [~]20,000 participants, we integrated plasma proteomics a...

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