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Age-Associated Structural Decline is Linked to Arterial Flow Territories in the Brain: Insights from Lifespan Human Connectome Project in Aging

2026-01-30 radiology and imaging Title + abstract only
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The effect of biological aging on brain structure is widespread and apparent. However, little is understood regarding which regions exhibit similarities in vulnerability, and what biological processes drive regional patterns of senescence-associated atrophy. Here, we investigated whether associations between age and brain structure exhibit distinct patterns of regional vulnerability, and if so, whether they are related to patterns of cerebral physiology which also show age-related decline. Using...

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