Optimizing Cognitive Performance Using Memory Enhancing Acute Intermittent Hypoxia (meAIH) in Young Healthy Adults: A Preliminary Study
Olsen, W. L.; Collins, M.; Jastrzembski, T. S.; Myers, C. W.
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The humans ability to acquire and retain novel information has been investigated via cognitive and physiological approaches. The current study employed a neruoplastic primer, acute intermittent hypoxia (AIH), to elicit beneficial changes in cognitive performance, specifically a declarative memory task, in young, healthy adults. It was hypothesized that participants who were exposed to a single session of a memory-enhancing acute intermittent hypoxia (meAIH; [~]10% oxygen) protocol would demonstrate enhanced performance on a declarative memory task when compared to a SHAM ([~]21% oxygen; control) group at an acquisition and one-week retention point. Results indicated that during the initial acquisition phase, the meAIH group performed significantly better on a declarative memory task than the SHAM group (p < 0.05), but not the retention phase. These novel results inform the understanding of cognitive neuroplasticity within young, healthy adults and how meAIH can be used to inform training paradigms for many populations.
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