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Comparing Fourteen Consensus Biomarkers of Aging: Epigenetic Pace of Aging as the Strongest Predictor of Mortality in BASE-II

2025-11-21 geriatric medicine Title + abstract only
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In many countries, lifespan has been increasing faster than healthspan, leading to more years spent with late-life disease and highlighting the need for reliable biomarkers to measure biological aging and to plan personalized interventions to extend healthspan. We used data from the Berlin Aging Study II (BASE-II, 60-80 years of age at baseline, average follow-up 7.4{+/-}1.5 years, range 3.9-10.4, n=1,083) to compare 14 biomarkers of aging recently consented by an expert panel for the use as out...

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