Back

eHealth Treatment Recommendations for the Common Cold across 13 European Countries: Correlation with Antibiotic Use

Huijghebaert, S.; Tilkin-Franssens, K.; Geerts, W.

2025-10-07 public and global health
10.1101/2025.10.06.25337441 medRxiv
Show abstract

BackgroundAntibiotic consumption (ABC) often ensues from patients misbelief that ABs are needed to treat the common cold. To test the impact of eHealth communication, the treatment recommendations on eHealth portals for patients/consumers were explored, modelled and correlated with ABC. MethodsCross-sectional study: identification of eHealth "common colds" pages (13 European countries); qualitative review of the treatment recommendations for antibiotics, nasal saline drops/irrigation, decongestants, other medicines; conversion to scores and correlation with ABC (ECDC-community sector 2022). Traditional use of saline was taken into account as co-variable. Resultse-sites generally explained why ABs are not needed, yet this message and position, as well as treatment e-recommendations highly differed. ABC differed by major treatment e-recommendations (p = .017), while a strong negative correlation was found between ABC and the treatment recommendation scores, indicating that ABC was lowest, if the eHealth site recommended saline first-line, while ABC increased if rather decongestants (no saline) were proposed, and even more, if emphasis on various medicines and complications (Spearman rs = -.945, p < .001). ConclusionsThe strong inverse correlation of ABC with SNI/treatment recommendations suggests that eHealth recommendations for the common cold may significantly affect ABC, and thus the patients need for ABs. The findings are in line with independent observations that the messages on prudent use of ABs need empowerment by offering patients effective symptom control. eHealth messages and solutions proposed need urgent further study as to change patients expectations and reduce ABC. Key pointsO_LIThe common cold is a major driver of antibiotic consumption (ABC) in the community. C_LIO_LIAnalysis of the common cold pages of 13 European public eHealth sites revealed they all discouraged ABs but the messages and position on the e-page highly differed. C_LIO_LIThe highly variable ABC strongly inversely correlated with recommendations for nasal saline (traditional use as co-variable). C_LIO_LIABC was lowest, if the eHealth site recommended nasal saline, yet increased if decongestants (no saline) first line, and even further if communicating many medicine options or complications. C_LIO_LIFindings confirmed that messages on prudent use of ABs need empowerment by offering an accessible effective alternative for symptom control. C_LIO_LIEducation of the public and physicians, and well-structured, persuasive public eHealth communication about the common cold, recommending nasal saline, may help to reduce ABC. Further research is warranted. C_LI

Matching journals

The top 7 journals account for 50% of the predicted probability mass.

50% of probability mass above

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.