Back

Decreased Mitochondrial Respiration in Peripheral Mononuclear Blood Cells in Chil-dren and Adolescents with Obesity and Type 2 Diabetes Mellitus

2025-10-02 endocrinology Title + abstract only
View on medRxiv
Show abstract

BackgroundThe prevalence of childhood obesity continues to rise worldwide. Obesity leads to major health risks already early in life, including insulin resistance (IR) and type 2 diabetes mellitus (T2DM). The pathogenesis of these conditions includes mitochondrial alterations, however, data on mitochondrial health in pediatric populations are scarce to date. MethodsThe study evaluated mitochondrial respiration in peripheral blood mononuclear cells (PBMCs) from children and adolescents (6-18 yea...

Predicted journal destinations