Clinical characteristics of 2025 Chikungunya outbreak in Chattogram, Bangladesh

Introduction and ObjectivesChikungunya fever became as a major outbreak in the year 2025 in Chattogram, Bangladesh. Objectives of the present study is to document the clinical profile of the Chikungunya affected patients in Chattogram, Bangladesh. MethodsThis is a cross sectional observational study conducted in a period of three months from June 2025 through August 2025 among the clinical, serologically and/or virologically confirmed patients of Chikungunya. ResultsAmong the 120 patients female was more then the male (52.5% vs 47.5%). Mean age of the patients were found 45.34{+/-} 15. 37 years. Most common presentations were fever(81.66%), multiple joint pain (73.33%), ankle swelling and pain (35.83%), bodyaches (43.33%) and rashes (34.16%). Skin rash, nausea/vomiting, urticaria like skin lesions, nose pigmentations, ulcers, morning stiffness were found some as uncommon findings. Haematological study revealed Hb% was normal in 95% patients, leucopenia, neutropenia and lymphopenia were found in 18.33%, 10.83% and 57.50% respectively. Among all, 115(95.83%) had normal ranged platelet. Regarding serological findings Chikungunya IgM and IgG was found positive among 55.0% and 5.83% cases respectively. Regarding molecular data 42(35.0%) were found RT PCR for Chikungunya positive and 5 cases were found for both Chikungunya and Dengue positive. Among the study patients diabetes mellites, hypertension, Ischemic heart disease were found common comorbidities which were 14.1%, 13.3% and 7.5% respectively. One patient was found with RA which made dilemma with post chikungunya arthritis ConclusionChikungunya fever showed varied clinical features, serological and molecular findings in 2025 outbreak in Chattogram, Bangladesh.