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Serum-derived extracellular vesicles as biological indicator of mobility resilience in older adults

2025-09-12 geriatric medicine Title + abstract only
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The decline in mobility with aging is a major health concern, associated with a high risk for disability. Despite the widespread prevalence of gait slowing in elderly adults, this issue has not been adequately addressed. The central nervous system and skeletal muscle system are key regulators of gait speed. However, direct molecular communication along the brain-muscle axis and the role of these interactions in mobility resilience remain poorly studied. Recently, extracellular vesicles (EV), mem...

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