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Evidence-Based Interventions Across the Life Course for Healthy Aging: A Scoping Review made in Colombia

Gonzalez, L. M.; Mojica, L. E.; Riveros, S.; Vanegas, V.; Otero, M.; Gomez, A.; Lopez, V. V.; Ramirez, L. M.; Sanchez, V.; Chaves, F.; Jaimes, M. A.

2025-08-19 psychiatry and clinical psychology
10.1101/2025.08.18.25333703 medRxiv
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BackgroundPopulation aging is a major demographic challenge, particularly in low- and middle-income countries, where the burden of chronic and neurocognitive conditions is projected to grow sharply. ObjectivesThis scoping review aimed to synthesize scientific evidence on interventions that promote healthy aging across the life course. It was conducted following the Joanna Briggs Institute PCC framework. MethodsA systematic search was performed across PubMed, Scielo, EMBASE, PsycINFO, Cochrane, and LiLACS, without language or date restrictions. ResultsFrom 5,808 records screened, 219 studies met the inclusion criteria, comprising systematic reviews, meta-analyses, clinical trials, quasi-experimental, and observational studies. Interventions were classified by thematic domains, including physical and mental health, social participation, education, technology, nutrition, public policy, and cultural aspects. ConclusionsMost studies focused on adult and older populations, with physical and mental health representing the predominant areas addressed, while other dimensions were less represented. Significant gaps remain regarding racially diverse populations, advanced-aged older adults, genetic stratification, and life-course perspectives, underscoring the need for diversified research designs to guide equitable and comprehensive healthy ageing strategies.

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