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Plasma levels of soluble podoplanin are higher in acute promyelocytic leukemia compared to other forms of acute myeloid leukemia
2025-07-30
hematology
Title + abstract only
View on medRxiv
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Backgroundacute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) marked by a high incidence of coagulopathy. Podoplanin (PDPN), a glycoprotein involved in platelet activation through interaction with CLEC-2, has been recently identified on leukemic promyelocytes and suggested as a potential contributor to APL coagulopathy. Identification of novel biomarkers and therapeutic targets for APL coagulopathy can potentially improve the outcomes of this condition. Aimto explore...
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