Risk Factors for Non-Syndromic Cleft Lip and Palate: A Cross-Sectional Study
Chowdhury, M. M.; Chowdhury, M.; Tabassum, N.; Ahsan, A. H. M. M.; Tanni, F.; Das, B. K.; Karim, A. M. M. N.
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ObjectivesOrofacial clefts are among the most common congenital craniofacial anomalies, with non-syndromic forms (NSCL/P) accounting for the majority of cases. In Bangladesh, an estimated 275,000 to 300,000 individuals are affected, many lacking access to timely surgical or preventive care. Study DesignThis cross-sectional study examined potential contributing factors to NSCL/P among children at the pediatric surgery unit of Care Hospital in Mohammadpur, Dhaka. Data were collected over a 12-month period through structured interviews. MethodsA total of 400 children with clinically confirmed NSCL/P were included. Questionnaires captured data on demographic characteristics. Univariate and multivariate analyses were conducted to identify associations risk factors. ResultsBoth analyses revealed that young maternal age, low maternal education and delay fatherhood associated with increased risk. ConclusionsThese findings highlight the role of socioeconomic and demographic factors in the occurrence of NSCL/P. The results have implications for health professionals and public health, specifically, early identification of at-risk groups.
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