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Examining Cognitive Predictors of Static Balance in Older Adults: The Role of Global Cognition and Inhibition: A cross-sectional study

Divandari, N.; Bird, M.-L.; Zoghi, M.; vakili, F.; Jaberzadeh, S.

2025-04-28 geriatric medicine
10.1101/2025.04.24.25326312 medRxiv
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Background and ObjectivesFalls are a critical public health issue, with postural balance being key to prevention. While cognition is known to influence balance, the cognitive domain most strongly associated with static balance, and its ability to predict balance performance independently of age, remains unclear. Research Design and MethodsSixty-two healthy older adults (mean age 74 {+/-} 8.6 years) participated in this cross-sectional study. Static balance was assessed using the Sway Medical App, and cognitive domains were evaluated through global cognition (Mini-Mental State Examination), inhibition (Stroop test), working memory (N-back test), and processing speed (Deary-Liewald test). Hierarchical multiple regression was applied to analyse cognitive predictors of static balance. ResultsHigher cognitive performance correlated with better balance. Global cognition and inhibition significantly predicted static balance beyond age, while processing speed and working memory were not significant predictors. Discussion and ImplicationsGlobal cognition and inhibition may serve as biomarkers for early detection of balance impairments. Incorporating assessments of global cognition and inhibition into balance evaluations could guide targeted interventions to reduce fall risks and enhance mobility in older adults.

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