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Revisiting insulin resistance in human cancer cachexia - a systematic review and meta-analysis

2025-03-31 endocrinology Title + abstract only
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BackgroundApproximately half of all patients with cancer experience unintentional weight loss called cancer cachexia (CAC), which reduces overall survival and impairs quality of life. Metabolic dysfunction is frequently observed in patients with cancer, likely due to insulin resistance. Due to its anabolic effects, insulin resistance could be implicated in the progression of CAC. However, comprehensive clinical data in human populations remain limited, and the potential association between insul...

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