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Epigenetic entropy, social disparity, and health and lifespan in the Women's Health Initiative

2025-02-23 epidemiology Title + abstract only
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ABSTRACTThe pace of aging varies between individuals and is marked by changes in DNA methylation (DNAm) including an increase in randomness or entropy. Here, we computed epigenetic scores of aging and entropy using DNAm datasets from the Womens Health Initiative (WHI). We investigated how different epigenetic aging metrics relate to demographic and health variables, and mortality risk. Income and education, two proxies of socioeconomics (SE), had consistent associations with epigenetic aging and...

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