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The association of gut microbiome composition with musculoskeletal features in middle-aged and older adults: a two-cohort joint study

2025-02-21 endocrinology Title + abstract only
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BackgroundBones and muscles are connected anatomically, and functionally. Preliminary evidence has shown the gut microbiome influences the aging process of bone and muscle in animal studies. However, such evidence in humans is still scarce. This study aimed to assess the microbiome-bone and microbiome-muscle associations in two cohorts of community-dwelling older adults. MethodsWe leveraged information from two large population-based cohorts, i.e., the Rotterdam Study (mean age 62.7 {+/-} 5.6 y...

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