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Prognostic Model Construction Based on Platinum-Free Interval in Ovarian Cancer and Its Implication for Chemotherapy Resistance

2024-12-03 oncology Title + abstract only
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BackgroundWhile platinum sensitivity and resistance have long been central to treatment decisions in high-grade serous ovarian cancer (HGSOC), these categories are increasingly questioned in real-world clinical settings. This study seeks to develop a prognostic model based on platinum-free interval (PFI) as a reliable indicator of patient prognosis, with additional exploration of chemotherapy resistance-related genes and pathways. Methods70 HGSOC patients with varied gene expression profiles an...

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