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The Role of p16Ink4a as an Early Predictor of Physiological Decline during Natural Aging
2024-11-22
geriatric medicine
Title + abstract only
View on medRxiv
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Cellular senescence is a prominent accomplice of aging. The expression of gene p16ink4a has been established as a biomarker of cellular senescence in humans and animal models. However, it has not been extensively studied in clinical settings in the context of natural aging and the development of age-related diseases. Here, we report the results of a natural aging study that provided an assessment of cellular senescence and a battery of measures of clinical status, quality of life (QOL), and phys...
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