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Mathematical modeling of the frozen zone dynamics: towards using thermal imagers in cryotherapy

Ivakhnenko, O. V.; Todrin, O. F.; Globa, V. Y.; Chyzh, M. O.; Kovalov, G. O.; Shevchenko, S. N.

2024-10-22 scientific communication and education
10.1101/2024.10.19.619201 bioRxiv
Show abstract

Using thermal imaging for cryoablation and cryotherapy is a convenient technique but it does not allow for visualization of what is inside. We model thermal field distribution which can help relate surface thermal field images to in-depth temperature field dynamics that show freezing and thawing processes dynamics. We consider the spatio-temporal distribution of temperature using examples of hydrogel and living tissue subjected to a cryoprobe. Freezing in the hydrogel is compared with the measurements using visual morphometry. Such studies can be useful for comparing in-vitro and in-vivo thermal field dynamics and for estimating the correct timing for cryoapplication.

Published in PLOS ONE (predicted rank #1) · training set

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