The First Comprehensive Forensic Genetic Study Of A Member Of Christopher Columbus' Family: His Great-Great-Grandson
Navarro Vera, I.; Yravedra Saez de los Terreros, J.; Bonilla, A.; Tirapu, M.; Albert, M.; Jimenez, P.; Herranz, D.; Garcia, C.
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The present study has successfully obtained genetic information that allow the identification from direct descendants of Christopher Columbus, dating from 1526 to 1734. This represents the first achievement of this unique objective. The results obtained from the analysed samples, characterized by their significant antiquity, yield exceptional insights into forensic genetics and its newest protocols and methodologies applied to the study of ancient skeletal remains. This work presents the preliminary results of the whole family study using massive parallel sequencing, focusing on the autosomal Single Nucleotide Polymorphism (SNP) and Short Tandem Repeats (STR) markers, including their flanking region sequences, as well as ancestry informative markers (AIMS) of the great-great-grandson of the discoverer. The results of this project pave the way towards the application of new sequencing technologies for the study of genetic evolution, biogeographical origins and forensic identification of historical characters.
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