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The bioavailability of compounded and generic rapamycin in normative aging individuals: A retrospective study and review with clinical implications
2024-08-16
pharmacology and therapeutics
Title + abstract only
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Rapamycin, also known as sirolimus, has demonstrated great potential for application in longevity medicine. However, the bioavailability of generic and compounded rapamycin at longevity doses in normative aging individuals remains unknown. We conducted a retrospective, real-world study determining the 24-hour blood rapamycin levels to establish the relative bioavailability, dose-to-blood level linearity and inter-individual heterogeneity in a normative aging cohort. Participants received either ...
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