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Acute Kidney Injury As A Predictor Of In-Hospital Mortality In Patients With A Diagnosis Of Severe COVID-19

Cruz Ordinola, A.; Fajardo Arriola, C.; Sandoval Ato, R.

2024-06-01 nephrology
10.1101/2024.05.31.24308297 medRxiv
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OBJECTIVEDetermine if Acute Kidney Injury (AKI) is a predictor of In-hospital Mortality in severe Covid-19 patients. METHODSA retrospective cohort study was carried out with severe Covid-19 patients from the Hospital de la Amistad Peru - Corea Santa Rosa II - Piura, using a multivariate analysis with the bivariate logistic regression technique and the method = Advance by steps (ratio of likelihood), to calculate a predictive model for Mortality in Covid-19 patients exposed to ARI. RESULTSMortality was higher in the cohort exposed to ARI (95% vs 71.9%) and a 5-fold RR of death in the patient exposed to ARI compared to the Covid-19 patient not exposed to ARI. CONCLUSIONExposure to ARI increases the risk of mortality by 5 times, increasing the risk of mortality based on the increase in the SOFA score upon admission to the ICU and increase in mg/dl of C-Reactive Protein.

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