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The Seasonal Influenza Vaccine Cannot Trigger a Titer Increase Among Some Elderly Individuals

Ge, Y.; Cao, W.; Sun, S.; Ross, T. M.; Shen, Y.

2024-01-18 epidemiology
10.1101/2024.01.17.24301451 medRxiv
Show abstract

Many elderlies exhibited absent responses to influenza vaccines. Our exploration of this heterogeneity revealed associations with vaccine dose (HD vs. SD, OR: 0.59 (95%CrI, 0.4 to 0.87)), pre-vaccination titer levels (OR: 1.57 (95%CrI, 1.38 to 1.8), and gender (Male vs. Female OR: 2.12 (95%CrI, 1.38 to 3.25)).

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