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Associations between regional adipose tissue distribution and skeletal muscle bioenergetics in older men and women
2023-11-11
geriatric medicine
Title + abstract only
View on medRxiv
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ObjectiveExamine the association of ectopic adipose tissue (AT) with skeletal muscle (SM) mitochondrial bioenergetics in older adults. MethodsCross-sectional data from 829 older adults [≥]70 years was used. Total abdominal, subcutaneous, and visceral AT; and thigh muscle fat infiltration (MFI) was quantified by MRI. SM mitochondrial energetics were characterized using in vivo 31P-MRS (ATPmax) and ex vivo high-resolution respirometry (maximal oxidative phosphorylation (OXPHOS)). ActivPal was ...
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