A Systematic Review : Cardiovascular Effects Of Systemic Sclerosis
PANJIYAR, B. K.; Panchumarthi, D.; BATHULA, S.; MADAM, S. T.; Nemani, R. R. S.
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Systemic sclerosis is a connective autoimmune disorder characterized by the deposition of an extracellular matrix in the internal organs leading to fibrosis and damage to internal organs. Cardiovascular effects of systemic sclerosis include arrhythmias, coronary artery disease, valvular diseases, pericardial diseases, atherosclerosis, myocardial diseases. Thus it also has a fatal effect on the cardiovascular system making it significant to know its epidemiology, pathophysiology, screening techniques, and investigations which help in early diagnosis of the cardiac lesions of systemic sclerosis. Cardiovascular effects of systemic sclerosis is a multidisciplinary approach by a rheumatologist, cardiologist and radiologist. We reviewed 182 articles from renowned journals taken from google scholar and pubmed published between 2010 and 2023 of which 8 articles are focused for in depth review. This systematic review summarizes the effects of systemic sclerosis on cardiovascular system ranging from arrhythmias to pericardial diseases in brief including the pathogenesis, investigations and epidemiology.
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