Quinoa as Functional Food? Urinary elimination of ecdysterone after consumption of quinoa alone and in combination with spinach
Isenmann, E.; Yuliandra Yusuf, T.; Touvleliou, K.; Broekmann, M.; de la Torre, X.; Botre, F.; Diel, P.; Parr, M. K.
Show abstract
The phytosteroid ecdysterone is included on the monitoring list of the World Anti-Doping Agency. Therefore, the consumption of food rich in ecdysterone is the focus of a lively debate. Thus, urinary excretion of ecdysterone and its metabolites in humans was investigated following quinoa consumption alone and in combination with spinach. After intake of both preparations, ecdysterone and two metabolites were excreted in urine. Maximum concentrations of ecdysterone ranged from 0.44-5.50{micro}g/mL after quinoa and 0.34- 4.09{micro}g/mL after quinoa with spinach. The total urinary excreted amount as parent drug plus metabolites was 2.60(1.09)% following quinoa and 1.71(0.86)% after combination. Significant differences were found in total urinary excreted amounts of ecdysterone, 14-deoxy-ecdysterone, and 14-deoxy-poststerone. In conclusion, only small proportions of ecdysterone from quinoa and the combination with spinach were excreted in urine. The results indicate that both, quinoa and spinach, are poor sources of ecdysterone.
Matching journals
The top 8 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Comparison of blood and urine concentrations of equol by LC‒MS/MS method and factors associated with equol production in 466 Japanese men and women 95%
- Nutritional analysis of commercially available, complete plant- and meat-based dry dog foods in the UK 93%
- Combinatorial effects of Zingiber officinale and Citrus limon juices: Hypolipidemic and antioxidant insights from in vivo, in vitro, and in silico investigations 93%
Similar papers in this journal
- Pharmacokinetics of caffeine: A systematic analysis of reported data for application in metabolic phenotyping and liver function testing 93%
- Anti-inflammatory properties of chemical probes in human whole blood: focus on prostaglandin E2 production 91%
- Hydroxychloroquine increased psychiatric-like behaviors and disrupted the expression of related genes in the mouse brain 90%
Similar papers in this journal
- Controlled Administration of Dehydrochloromethyltestosterone in Humans: Urinary Excretion and Long-Term Detection of Metabolites for Anti-Doping Purpose 94%
- Mass Spectrometry Reveals that Oxysterols are Secreted from Non-Alcoholic Fatty Liver Disease Induced Organoids 90%
- Differential effects of variations in human P450 oxidoreductase on the aromatase activity of CYP19A1 polymorphisms R264C and R264H 90%
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.