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Profiling an integrated network of cellular senescence and immune resilience measures in natural aging: a prospective multi-cohort study
2023-08-28
primary care research
Title + abstract only
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BackgroundBiological aging begins decades before the onset of age-related clinical conditions and is mediated by both cellular senescence and declining adaptive immune function. These processes are functionally related with the rate of senescent cell accumulation dependent upon a balance between induction and immune clearance. We previously showed that biomarkers in these domains can identify patients at-risk of surgery-related adverse events. Here, we describe evidence of clinical relevance in ...
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