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Predicting risk of Alzheimer's disease using polygenic risk scores developed for Parkinson's disease
2023-08-21
genetic and genomic medicine
Title + abstract only
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Background and ObjectivesThe two most common neurodegenerative diseases are Alzheimers disease (AD) and Parkinsons disease (PD), both related to age and affect millions of people across the world, especially as life expectancy increases in certain countries. Here, we explore the potential predictiveness of the genetic risk of AD and PD separately and then the extent of the underlying shared genetics of AD and PD. MethodsThe population genetic risk estimates for AD and PD were derived using a pr...
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