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Apolipoprotein A1 levels and its association with NS1 in the pathogenesis of acute dengue
2022-07-22
infectious diseases
Title + abstract only
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BackgroundThe dengue NS1 antigen is a secretory protein and was shown to associate with apolipoprotein A1 (ApoA1). Therefore, we sought to investigate the changes in ApoA1 levels in patients with varying severity of acute dengue and then proceeded to investigate how ApoA1 and NS1 interactions affect cytokine production from primary human monocytes. Methodology/Principal FindingsSerial measurements of ApoA1, viral loads, NS1 antigen levels and lipid profiles were done in adult patients with deng...
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