Is Mycobacterium avium subspecies paratuberculosis (MAP) associated with Crohn's Disease?
Patterson, J. M.; Winstead, C.; Milligan, K.
Show abstract
ObjectiveThis retroactive meta-analysis assesses the relationship between Mycobacterium avium subspecies paratuberculosis (MAP) and Crohns Disease (CD). MethodsA meta-analysis of PCR- and culture-based studies was conducted to determine if there is a relationship between MAP and Crohns Disease. The chi-squared test of independence was also conducted to determine if MAP infection and Crohns disease onset are independent events. ResultsThe studies analyzed were able to provide evidence that Mycobacterium avium subspecies paratuberculosis is highly associated with Crohns disease. It is also shown that, regardless of detection method, MAP can effectively be detected in Crohns patients. ConclusionMAP is strongly connected with Crohns Disease. SummaryThis paper examines the incidence of MAP in the tissue of Crohns disease patients. We found evidence to support MAP being strongly associated with Crohns disease.
Matching journals
The top 6 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Prevalence and Factors Associated with Celiac Disease in High-Risk Patients with Functional Gastrointestinal Disorders 93%
- Systematic Review Protocol of aetiology of mechanical bowel obstruction in Low-and-middle income countries: Has anything changed in the last two decades? 92%
- Smear positive tuberculosis and genetic diversity of M. tuberculosis isolates in individuals visiting health facilities in South Gondar Zone, northwest Ethiopia 92%
Similar papers in this journal
- Relationship Between Patient Sex and Serum Tumor Necrosis Factor Antagonist Drug and Anti-Drug Antibody Concentrations in Inflammatory Bowel Disease; A Nationwide Cohort Study 91%
- Evaluation of Natural and Botanical Medicines for Activity against Growing and Non-growing Forms of B. burgdorferi 90%
- Is the infection of the SARS-CoV-2 Delta variant associated with the outcomes of COVID-19 patients? 89%
Similar papers in this journal
- Protein and Microbial Biomarkers in Sputum Discern Acute and Latent Tuberculosis in Investigation of Pastoral Ethiopian Cohort 91%
- Performance of microbiological tests for tuberculosis diagnostic according to the type of respiratory specimen: a 10-year retrospective study 90%
- Enteropathogenic Escherichia coli (EPEC) Infection Induces Diarrhea, Intestinal Damage, Metabolic Alterations and Increased Intestinal Permeability in a Murine Model 90%
Similar papers in this journal
Similar papers in this journal
- Environmental enteric dysfunction and small intestinal histomorphology of stunted children in Bangladesh 92%
- The Accuracy of Histopathological and Cytopathological Techniques in the Identification of the Mycetoma Causative Agents 92%
- B-1 cell-mediated modulation of M1-macrophage profile can ameliorate microbicidal functions and disrupt the evasion mechanisms of Encephalitozoon cuniculi 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.