A study of sociodemographic and clinical profiles of HIV-1 infected North Indian patients

The aim of this study was to analyze the sociodemographic, clinical, immunologic, and risk factors of drug-resistant (>1000 copies/ml) and virologically suppressed (<1000 to <40 copies /ml to target not detected levels) patients at the ART center, Sarojini Naidu Medical College, Agra, North India. A total of 193 patients on first-line antiretroviral therapy were included those were recruited from December 2009 to November 2016. The patients included in this study had a CD4 cell count of [&le;] 350 cubic/mm. The details of Demographic, clinical, and social factors were collected in a patient information leaflet and statistically analyzed. After viral load, two groups of patients were observed. The drug-resistant group (N=58) had a viral load [&ge;]1000 copies/ml and virologically suppressed group (N=135) had a viral load <1000 copies/ml to target not detected level. A comparison statement result was presented in both groups of drug-resistant and virologically suppressed patients. Males were observed in the highest frequency (42, 72.41%). The heterosexual mode of transmission was predominant (40, 68.96%, and 98,72.59%). The highest number of married couples and illiterates in the two groups. Tuberculosis was observed in the highest numbers in the two groups. The analysis of socioeconomic factors of North Indian patients will be a concern issue in the demographic profiles of HIV-1 patients. The clinical features, analysis would help clinicians in further therapy implementation, monitoring CD4 and Viral load counts of North Indian patients.