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The expression of PDCD1 and CD274 in T cells and macrophages correlated positively with COVID-19 severity

Gao, Q.; Liu, S.; Ding, R.; Chen, H.; Dong, X.; Xie, J.; Li, Y.; Chen, L.; Liu, H.; Mu, F.

2020-11-18 immunology
10.1101/2020.11.17.378992 bioRxiv
Show abstract

The immune responses underlying the infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain unclear. To help understand the pathology of coronavirus disease 2019 (COVID-19) pandemics, public data were analyzed and the expression of PDCD1 (encoding PD-1) and CD274 (encoding PD-L1) in T cells and macrophages were identified to correlate positively with COVID-19 severity.

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