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Cardiac Arrhythmias in Patients with COVID-19: A Systematic review and Meta-analysis

Hamam, O.; Goda, A.; Eldalal, M.; Ussama, A.; Elmandouh, O.; Fahmy, M.; Elyamany, K.; Ikram, W.; Mahdy, A.; Bhandari, R.; Asal, H.; Egbe, A.

2020-10-13 cardiovascular medicine
10.1101/2020.10.09.20209379 medRxiv
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BackgroundCardiac arrhythmia cannot be overlooked in patients with coronavirus disease 2019 (COVID-19) as it carries a great influence on the outcomes. Hence, this study aimed to build concrete evidence regarding the incidence of cardiac arrhythmia in patients with COVID-19. MethodsWe performed a systematic search for trusted databases/search engines including PubMed, Scopus, Cochrane library and web of science. After screening, the relevant data were extracted and the incidences from the different included studies were pooled for meta-analysis. ResultsNine studies were finally included in our study consisting of 1445 patients. The results of meta-analysis showed that the incidence of arrhythmia in patients with COVID-19 was 19.7% with 95% confidence interval (CI) ranging from 11.7 to 27.6%. There was also a significant heterogeneity (I2{square}={square}94.67%). ConclusionCardiac arrhythmias were highly frequent in patients with COVID-19 and observed in 19.7% of them. Appropriate monitoring by electrocardiogram with accurate and early identification of arrhythmias is important for better management and outcomes. HighlightsO_LICardiac arrhythmia cannot be overlooked in patients with coronavirus disease 2019 (COVID-19) as it carries a great influence on the outcomes. C_LIO_LIThis study aimed to build concrete evidence regarding the incidence of cardiac arrhythmia in patients with COVID-19. C_LIO_LICardiac arrhythmias were highly frequent in patients with COVID-19 and observed in 19.7% of them. C_LIO_LIAppropriate monitoring by electrocardiogram with accurate and early identification of arrhythmias is important for better management and outcomes. C_LI

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