Anti-oxidant and in-vitro α-amylase inhibitory activities of leaves and barks of Randia dumetorum

The process of drug discovery and development in the world over a recent year has been increasingly shaped by the formulaic approaches and natural products, prioritized by popular pharmaceutical industries. In many countries like Nepal, Randia dumetorum (Maidal) is one of the popular alternatives for overcoming various symptoms such as acidity, food poisoning ulcers, diabetes and ulcers. It has been using by the people because of its wide range of therapeutic uses. Though, the considerable research had been conducted to reveal the biologically active compounds and its pharmacological effect, the rich constituent of this plant and its major biological perspective was yet to be studied comprehensively. Accordingly, the main focus of this study was the alpha amylase inhibition of methanolic extracts obtained from leaves and barks of Randia dumetorum plant. The plant extracts were obtained by dissolving dried plant with 100% methanol overnight and evaporating to the dryness. The obtained plant extract was used to study mentioned biological activities. The results obtained showed that the extract obtained from leaves and barks showed antioxidant and alpha amylase inhibition activities. This research can be helpful to discover new types of therapeutics in the future.