Research on the relationship between postoperative D-dimer Clearance and Trauma infection complications in patients with different degrees of fracture

BackgroundOccurrence of thrombotic disease after orthopedic surgery has always been an important issue affecting the prognosis of patients. In this paper, retrospective analysis was used to analyze the D-dimer clearance rate after different degrees of fractures, suggesting that the D-dimer clearance rate can be used as an index to evaluate thrombotic diseases after orthopedic surgery. Material/MethodsSeventy-five patients with orthopedic surgery were randomly selected from March to June 2017. According to the degrees of fractures and complications, they were divided into SF(single fracture), MF(multiple fracture), FCI(Fracture combined with infection)three groups, 25 in each group.D-dimer results of each case on 1 day, 2 days, 3 days, 4 days, 5 days, and 7 days after orthopedic surgery were recorded and counted.The slope of correlation equation of D-dimer value according to time is the D-dimer clearance rate. ResultsThe D-dimer clearance rate in the SF{square}JMF {square}FCI group was -0.0490, -0.0502 and -0.0692{square}The P value is respectively 0.0049, 0.0061 and 0.0163, the difference is significant. ConclusionsAfter traumatic fracture surgery, whether D-dimer clears at a normal rate is closely related to its outcome. Decreasing D-dimer clearance is related to postoperative infections and thrombotic diseases. D-dimer clearance can be used as an important parameter and observation index for judging the clinical outcome of patients with complications such as severe trauma and infection. At the same time, we can further study the cut-off value of D-dimer clearance.