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Radiation associated brain image changes after proton therapy for skull base head and neck cancers.

2020-02-09 oncology Title + abstract only
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Background and purposeTo characterize patterns and outcomes of brain MR image changes after proton therapy (PT) for skull base head and neck cancer (HNC). Material and methods127 patients treated with PT for HNC who had received at least 40 Gy(RBE) to the brain and had [≥] 1 follow-up MRI > 6 months after PT were analyzed. MRIs were reviewed for radiation- associated image changes (RAIC). MRIs were rigidly registered to planning CTs, and RAIC were contoured on T1 (post-contrast) and T2 weigh...

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