When Words Sound Alike: Decoding Homophone Processing in Chinese Primary Progressive Aphasia
Tee, B. L.; Chen, T.-F.; Li-Ying, L. K.-C.; Chuang, Y.; Lo, R. Y.; Tsoh, J.; Chan, A. L.-T.; Wong, A.; Mok, V.; Yan, T. Y. C.; Lu, C. J.; Yu, Y.; Lee, Y.; Allen, I. E.; Leng, F.; Cheng, Y.-W.; Lin, C.-H.; Li, C.-H.; Chen, Y.; Zhou, G.; Ng, A.; Vonk, J.; Gorno-Tempini, M. L.
Show abstract
Chinese is one of the living languages with the highest homophone densities, making homophone processing a critical component of language comprehension and orthographic decoding, as well as an ideal model for examining its cognitive mechanisms. This study assessed mono- and bi-character homophone selection function in 129 Mandarin- and Cantonese-speaking participants, including 66 cognitively healthy individuals, 17 with semantic variant (sv) primary progressive aphasia (PPA), 23 with the nonfluent/agrammatic variant (nfv) PPA, and 23 with the logopenic variant (lv) PPA. All PPA variants showed impairment in homophone selection, with most significant deficits in svPPA and lvPPA. ROC analyses demonstrated its strong diagnostic utility for distinguishing PPA from controls. Voxel-based morphometry revealed that homophone performance correlated with gray-matter volume in left anterior and inferior temporal regions, with variant-specific patterns observed. These findings described the potential role of homophone selection in diagnosing PPA syndrome in Chinese speakers, illuminate crosslinguistic influences on language impairment in PPA, and provide novel insights into the cognitive processing of homophones.
Matching journals
The top 9 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Going off the rails: Impaired coherence in the speech of patients with semantic control deficits 94%
- White matter connectivity in uncinate fasciculus accounts for visual attention span in developmental dyslexia 92%
- Distinctive neural correlates of phonological processing and reading impairment in fetal alcohol-exposed adolescents with and without facial dysmorphology 92%
Similar papers in this journal
- Hearing and cognitive decline in aging differentially impact neural tracking of context-supported versus random speech across linguistic timescales 93%
- How long is long? Word length effects in reading correspond to minimal graphemic units: An MEG study in Bangla 92%
- Brain activations during execution and observation of visually guided sequential manual movements in autism and in typical development: A study protocol 91%
Similar papers in this journal
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.