Back

PFAS and phthalates in follicular fluid of a Nebraska in vitro fertilization (IVF) cohort

Taiba, J.; Balu, N.; Castillo, A. C.; Barakat, R.; Lee, C.; Chen, A.; Gustin, S.; Constance, E.; Davis, J. S.; Bell, J. E.; Clark, K. L.

2026-09-29 obstetrics and gynecology
10.64898/2026.09.21.26363443 medRxiv
Show abstract

Per- and polyfluoroalkyl substances (PFAS) and phthalate metabolites are understudied in follicular fluid of women undergoing assisted reproduction. We characterized these in previously collected follicular fluid from patients at a Nebraska fertility clinic (August 2022 to June 2025) and retrieved demographics and clinical characteristics from fertility records. Spearman correlations and nonparametric tests evaluated PFAS and phthalate correlations and exposure differences by age, race, BMI, and urbanicity. Seven PFAS and four phthalate metabolites were detected in at least half of participants. PFOS and PFHxS concentrations were higher in younger women, and mono-isobutyl phthalate (MiBP) was higher in younger and non-White women. PFAS and phthalate correlations were weak, and exposures did not differ by urbanicity, indicating multiple chemical exposures in follicular fluid with sociodemographic disparities.

Matching journals

The top 6 journals account for 50% of the predicted probability mass.

1
Human Reproduction
◐ 20 papers in training set
Top 0.1%
13.9%
Similar papers in this journal
2
Scientific Reports
○ 3612 papers in training set
Top 2%
13.7%
Similar papers in this journal
3
PLOS ONE
● 5266 papers in training set
Top 19%
8.5%
Similar papers in this journal
4
International Journal of Environmental Research and Public Health
○ 128 papers in training set
Top 0.4%
7.3%
Similar papers in this journal
5
Environmental Science & Technology
● 64 papers in training set
Top 0.3%
4.4%
Similar papers in this journal
6
Environment International
○ 43 papers in training set
Top 0.2%
3.7%
50% of probability mass above
7
Environmental Research
○ 49 papers in training set
Top 0.3%
3.5%
8
Ecotoxicology and Environmental Safety
○ 10 papers in training set
Top 0.1%
2.6%
9
Toxicological Sciences
◐ 41 papers in training set
Top 0.2%
2.3%
10
Computational and Structural Biotechnology Journal
● 242 papers in training set
Top 3%
1.9%
11
Chemosphere
○ 17 papers in training set
Top 0.2%
1.8%
12
Nature Communications
○ 5641 papers in training set
Top 44%
1.8%
13
Journal of the Endocrine Society
● 15 papers in training set
Top 0.1%
1.6%
14
Metabolites
○ 53 papers in training set
Top 0.6%
1.4%
15
Biology of Reproduction
◐ 36 papers in training set
Top 0.4%
1.4%
16
BMC Medicine
○ 176 papers in training set
Top 3%
1.2%
17
Applied Sciences
○ 25 papers in training set
Top 0.4%
1.2%
18
Science of The Total Environment
○ 186 papers in training set
Top 2%
1.2%
19
Heliyon
○ 152 papers in training set
Top 4%
1.2%
20
Archives of Public Health
○ 14 papers in training set
Top 0.2%
1.2%
21
JAMIA Open
◐ 42 papers in training set
Top 1%
1.2%
22
Frontiers in Cell and Developmental Biology
○ 233 papers in training set
Top 3%
1.2%
23
JAMA Network Open
● 130 papers in training set
Top 3%
1.1%
24
Environmental Pollution
○ 37 papers in training set
Top 0.9%
1.1%
25
PeerJ
◐ 308 papers in training set
Top 10%
0.9%
26
eLife
● 5828 papers in training set
Top 64%
0.9%
27
International Journal of Molecular Sciences
○ 494 papers in training set
Top 13%
0.9%
28
iScience
○ 1154 papers in training set
Top 38%
0.7%
29
GENETICS
◐ 483 papers in training set
Top 5%
0.5%
30
BMJ Open
● 601 papers in training set
Top 13%
0.5%

"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.