New Serum Potassium Cut-Off Point for Improving Primary Aldosteronism Screening
Li, H.; Zhou, F.; Zhao, H.; Huang, W.; Wang, H.; Wang, S.
Show abstract
This study enrolled 152 hypertensive patients with an ARR > 3.7 to assess the relationship between the traditional hypokalemia cutoff (3.5 mmol/L) and primary aldosteronism (PA) screening, and to establish a new cutoff. Under the traditional cutoff, only 35.7% of PA patients presented with hypokalemia. ROC curve analysis identified a new cutoff of 4.22 mmol/L, which increased sensitivity from 35.7% to 77.5%, with a specificity of 91.1% and an AUC of 0.897. The findings indicate that the traditional cutoff is insufficiently sensitive, while the new cutoff markedly improves screening sensitivity and facilitates early detection of PA.
Matching journals
The top 3 journals account for 50% of the predicted probability mass.
Similar papers in this journal
- Hypertension Management Dynamics in Pediatric CKD: Insights from the 4C Study 95%
- Trends in Awareness, Antihypertensive Medication Use and Blood Pressure Control by Race and Ethnicity Among Adults with Hypertension in the United States: A National Health and Nutrition Examination Analysis from 2011 to 2018 95%
- Hypertensive Disorders of Pregnancy and Primary Aldosteronism 94%
Similar papers in this journal
- Factors Associated with Treatment-Resistant Hypertension: Results of a prospective observational Study 97%
- Within-visit Blood Pressure Variability in Children and Adolescents in the National Health and Nutrition Examination Survey (2013-2020) 95%
- Low blood pressure phenotype underpins the tendency to reflex syncope 94%
Similar papers in this journal
- Free cortisol and free 21-deoxycortisol in the clinical evaluation of congenital adrenal hyperplasia 91%
- Testicular microvascular flow is altered in Klinefelter syndrome and predicts circulating testosterone 90%
- Salivary profiles of 11-oxygenated androgens follow a diurnal rhythm in patients with congenital adrenal hyperplasia 90%
Similar papers in this journal
- Pool walking may temporarily improve renal function by suppressing renin-angiotensin-aldosterone system in pregnant women 93%
- Genetic Predictors of Blood Pressure Traits are Associated with Preeclampsia 93%
- The use of angiotensin-converting enzyme inhibitors but not angiotensin receptor blockers in hospitalized patients with COVID-19 is associated with a lower risk of mortality 92%
"Similar papers" are the closest papers from that journal in the model's embedding space. They show what the match is built on, but the ranking comes mostly from a classifier over the whole training set, not from these examples alone.