CORe Designer: a CRISPR design tool for proteome engineering
Das, A.; Grech, J.; Hung, S.; Wu, J.; Callafe, C.; Corrie, A.; Yeung, K.; Goodwin, I.; Yu, D.; Hassan, S.; Reid, K.; Storch, M.; Child, M. A.
Show abstract
Precision proteome engineering requires tools that leverage CRISPR technologies, yet most current design platforms remain gene-centric. To bridge this gap, we introduce CORe Designer. Featuring an intuitive graphical user interface, CORe Designer enables researchers to design guide RNAs and homology-directed repair templates in a protein-centric manner. By automating these workflows, CORe Designer enables the design of targeted mutagenesis experiments for precision proteome engineering to be completed in minutes.
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