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Alzheimers risk markers and resting-state dynamic functional connectivity: Cross-Sectional Findings from the AGUEDA Study

2026-02-26 epidemiology Title + abstract only
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Background and ObjectivesAlzheimers disease (AD) is characterized by early disruptions in brain connectivity. However, how genetic and biological markers of AD risk relate to dynamic functional connectivity (dFC) remains unclear. This study examined whether AD-related pathology, genetic risk, and blood-based biomarkers (BBMs) of neurodegeneration are associated with local and distant resting-state dFC patterns, and whether these relate to cognitive performance in cognitively normal older adults....

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