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Development and psychometric evaluation of The Index of Myalgic Encephalomyelitis Symptoms (TIMES) Part I: Rasch Analysis and Content Validity

2026-02-17 health systems and quality improvement Title + abstract only
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ObjectiveTo develop and psychometrically evaluate an assessment of symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) MethodsAn initial symptom list was devised from the relevant literature with the patient and clinician advisory groups. An online survey with 85 symptom items in eight domains was completed by people with ME/CFS. Each item had two response structures (assessing symptom frequency and severity on five-point scales). Rasch analysis assessed each domain for unid...

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