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Finite element simulation of the pharmacodynamic model for aflibercept and ranibizumab for the treatment of age related macular degeneration

2026-02-06 ophthalmology Title + abstract only
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Age related macular degeneration is known to be one of the major causes of irreversible blindness among the older generation. We present a mathematical model of partial differential equations for the therapy of this disease, which is based on the intravitreal injection of a drug into the vitreous body. For the treatment to work, the drug has to travel past the inner-limiting membrane into the retina and reduce the free vascular endothelial growth factor (VEGF) concentration by binding to at leas...

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