The Effect of Sufentanil Administration via Bolus or Infusion on Time-to-Extubation in Cardiac Surgery: A Prospective, Randomized Clinical Trial

2026-02-06 anesthesia Title + abstract only

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BackgroundIntraoperative opioid administration for cardiac surgery varies greatly, with most of this variability arising from anesthesiologist and institutional practices. Anesthesiologists administer intraoperative opioids via intermittent boluses and continuous infusions. Real-world data have shown infusion administration to be a strong determinant of high intraoperative opioid exposure, but whether bolus or infusion administration of sufentanil affects post-operative outcomes is unknown. Met...